Owing to the presence of microbial biofilm on the implant, the eradication of biofilm-associated infections poses a challenge for antibiotic therapies. The study aimed to investigate the efficacy and safety of the novel antibiotic agent TNP-2092 in the context of implant infections. In vivo, the periprosthetic joint infection (PJI) rats treated with antibiotics showed an increase in body weight and decrease in swelling, temperature,

TenNor and Mayo Clinic Researchers Publish Article on Biofilm Bactericidal Activity of TNP-2092

TenNor publishes article on TNP-2092 PO Potential Application in the Treatment of Gastrointestinal and Liver Disorders in ACS Infectious Disease.

TenNor’s article “Development of a Dual-Acting Antibacterial Agent (TNP-2092) for the Treatment of Persistent Bacterial Infections” published recently in the Journal of Medicinal Chemistry has been selected as ACS Editors’ Choice.